(To be selected as per Subject Specialization)
Inorganic Chemistry (Optional)
Section-D Organometallic Compounds of Main Group Elements: General characteristics of different types of main group organometallics, stability, routes of M-C bond formation: Oxidative addition, transmetallation, Carbanion halide exchange, metal-hydrogen exchange, metal hydride addition to alkenes, methylenations and by Aryl diazonium salts. Structure elucidation by spectral techniques like IR, NMR, Mossbauer for compound of Si, Ge, Sn, Pb, As, Sb, Bi and Te.
Physical Chemistry (optional)
Thermodynamics of liquid mixtures, Molecular interactions in liquid mixtures: Ion-ion interactions, Ion-dipoleinteractions, Dipole-dipole interactions, Ion-induced dipole interactions, Dipoleinduceddipole interactions, Quadruple-octuple interactions; specific interactions,hydrogen bonding, charge-transfer interactions and contact charge-transferinteraction. Thermodynamic of excess functions; excess molar volumes, excessmolar enthalpies, excess isentropic compressibilities, excess Gibbs free energy,excess heat capacity and their significance. Statistical theories of liquid mixtures;(i) Cell model (ii) Flory's theory (iii) Sanchez and Lacombe's theory.
Quantum mechanics The Born-Oppenheimer approximation, The Hellmann-Feynman theorem,Huckel molecular orbital (HMO) theory. Applications of HMO theory (i) to setup and solve secular equation ; (ii) to calculate resonance energy; (iii) to drawmolecular orbital energy diagram for (1) Ethylene molecule taking in toconsideration the overlap integral and (2) Pyrrole molecule. Determination ofresonance integral, "Beta" in HMO theory by (1) Ionization potential; (2) Electronicspectra and (3) delocalization energy methods.
Solid State Chemistry:Defects in crystals; Various types of defects in crystal; Thermodynamics ofSchottky and Frenkel defects formation; Colour centers; Non-stoichiometricdefects; Classification of solids; lattice energy; evaluation of Madelung constant(NaCl); calculation of repulsive potential exponent; Lattice heat capacity;Einstein and Debye model of lattice heat capacity; Debye T3 low.
Electrodics:Electron transfer under an interfacial electrical field; Butler-Volmer equation;electrode kinetic involving semiconductor solution interface; photoelectrochemistry;p-type photo-cathodes; n-type photo-anodes; Rate determiningstep in photo-electrochemical reaction; Ionic conductivity in solids; Solidelectrolytes; Fast-ion conductors, oxygen ion conductors, sodium ion conductors;Solid state ionic devices, Batteries: Lithium batteries; Sodium batteries; fuelcells; sensors.
Organic Chemistry (Optional)
Section - A
Stereo selective Synthesis Principle of stereo selectivity, 1,2- and 1,3-asymmetric induction, acyclicstereoselection, distereoselection in cyclic systems.Enantioselective synthesis: Enantioselective hydroboration,hydrogeantion, epoxidation, enantioselective synthesis via hydrazones.Role of enzymes in chiral synthesis.
Section - B
Disconnection approach of synthesis Introduction, main synthetic strategies, Synthetic strategies of 1,2- and1,4-difuntionalised compounds, Group disconnection, Umpolung Strategies, a-functionalisation of carbonyl compounds. Synthetic approach to cyclic systems.Retro synthetic and reconnection strategies. ReagentsPreparation and application of following reagents:Hypervalent iodine, organoboron reagents (IBBN, CATB, IpC2BH, PINB),Organosilicon compounds, Trifluoromethylsulphonates (triflates).
Section - C
General synthesis of(a) compounds with three or more heteroatoms in the ring(1,2,3)- and (1,2,4)-triazoles(1,2,4)- and (1,3,4)-oxadiazoles(1,2,5)- and (1,3,4)-thiadiazoles(1.2.3)-, (1,2,4)- and (1,3,5)-triazines. Tetrazoles and tetrazines.
(b) Bridgehead nitrogen containing compounds:
Imidazo [1,2-a] and [1,5-a]pyridines
Triazolo [1,5-a] pyridines
S-triazolo [3,4-b] [1,3,4] thiadiazoles
Imidazo [2,1-b] [1,3,4] thiadiazoles
S-triazolo [3,4-b] [1,3,4] thiadiazines
Thiazolo [3,2-b] [1,2,4] triazoles.
Section - D
Green Chemistry Basic principles of green chemistry, Application of non-conventionaltechniques in organic synthesis (ultrasonic, microwave and grinding).Solid statesynthesis and synthesis under solvent free conditions.Use of ionic liquids.Drug discovery and developmentA rational approach to drug design and drug development of following drugs:cimetidineoxamniquine.